Joen-Rong Sheu Selected Research

rutecarpine

5/2022	Anti-Inflammatory Mechanism of An Alkaloid Rutaecarpine in LTA-Stimulated RAW 264.7 Cells: Pivotal Role on NF-κB and ERK/p38 Signaling Molecules.
1/2022	Decreased Human Platelet Activation and Mouse Pulmonary Thrombosis by Rutaecarpine and Comparison of the Relative Effectiveness with BAY11-7082: Crucial Signals of p38-NF-κB.
10/2021	Rutaecarpine, an Alkaloid from Evodia rutaecarpa, Can Prevent Platelet Activation in Humans and Reduce Microvascular Thrombosis in Mice: Crucial Role of the PI3K/Akt/GSK3β Signal Axis through a Cyclic Nucleotides/VASP-Independent Mechanism.

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Joen-Rong Sheu Research Topics

Disease

23	Neoplasms (Cancer) 09/2021 - 08/2005
21	Thrombosis (Thrombus) 01/2022 - 04/2003
17	Inflammation (Inflammations) 12/2021 - 08/2005
12	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 04/2020 - 04/2006
12	Infarction (Infarctions) 01/2017 - 09/2002
10	Brain Ischemia (Cerebral Ischemia) 07/2017 - 04/2006
10	Ischemia 01/2017 - 09/2002
9	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 01/2009
9	Pulmonary Embolism 01/2022 - 06/2002
8	Stroke (Strokes) 04/2019 - 04/2011
8	Hypoxia (Hypoxemia) 01/2019 - 03/2007
8	Brain Injuries (Brain Injury) 07/2017 - 04/2006
7	Ischemic Stroke 04/2020 - 04/2011
7	Fibrosis (Cirrhosis) 10/2019 - 06/2009
7	Reperfusion Injury 01/2019 - 09/2002
4	Embolic Stroke 04/2020 - 01/2014
4	Shock 01/2019 - 08/2002
4	Thromboembolism 02/2016 - 06/2005
4	Melanoma (Melanoma, Malignant) 09/2015 - 04/2009
3	Pleural Effusion (Pleural Effusions) 10/2019 - 08/2005
3	Atherosclerosis 11/2018 - 04/2011
3	Brain Infarction 01/2017 - 01/2009
3	Wounds and Injuries (Trauma) 01/2017 - 01/2014
3	Neoplasm Metastasis (Metastasis) 01/2015 - 05/2011
3	Vascular Diseases (Vascular Disease) 12/2011 - 04/2006
3	Tachycardia (Tachyarrhythmias) 08/2011 - 08/2002
2	Obesity 05/2022 - 06/2019
2	Hemorrhage 09/2021 - 01/2014
2	Ulcer 01/2017 - 01/2014
2	Neurodegenerative Diseases (Neurodegenerative Disease) 04/2016 - 04/2014
2	Glioma (Gliomas) 02/2016 - 05/2011
2	Lung Injury 12/2015 - 12/2015
2	Tuberculosis (Tuberculoses) 01/2015 - 08/2005
2	Mitochondrial Diseases (Mitochondrial Disease) 07/2014 - 03/2010
2	Necrosis 11/2013 - 08/2011
2	Chondrosarcoma 04/2013 - 05/2011

Drug/Important Bio-Agent (IBA)

11	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2015 - 08/2005
10	andrographolideIBA 07/2017 - 12/2011
10	Neuroprotective AgentsIBA 07/2017 - 04/2006
9	Matrix Metalloproteinases (MMPs)IBA 07/2020 - 03/2010
9	Free RadicalsIBA 04/2016 - 08/2002
8	Adenosine Diphosphate (ADP)IBA 01/2022 - 06/2002
8	AntioxidantsIBA 03/2018 - 04/2003
8	Caspase 3 (Caspase-3)IBA 09/2014 - 03/2007
7	beta-thujaplicinIBA 01/2019 - 01/2013
7	Proteins (Proteins, Gene)FDA Link 09/2015 - 01/2009
7	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 09/2014 - 04/2006
6	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 09/2021 - 06/2005
5	Pharmaceutical PreparationsIBA 01/2022 - 01/2015
5	platonin (NK 19)IBA 04/2020 - 08/2002
5	Mitogen-Activated Protein KinasesIBA 01/2018 - 04/2003
4	Plasminogen Activator Inhibitor 1IBA 10/2019 - 08/2005
4	Histone Deacetylase InhibitorsIBA 04/2012 - 05/2011
3	rutecarpineIBA 05/2022 - 10/2021
3	FlavonoidsIBA 08/2018 - 02/2012
3	CollagenIBA 01/2018 - 01/2014
3	Therapeutic UsesIBA 07/2017 - 01/2010
3	Hydroxyl RadicalIBA 01/2017 - 04/2009
3	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2017 - 01/2014
3	cepharanthineIBA 12/2015 - 01/2015
3	CytokinesIBA 12/2015 - 01/2009
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2015 - 08/2002
3	sesamolIBA 02/2015 - 05/2011
3	Tissue Plasminogen Activator (Alteplase)FDA Link 09/2014 - 08/2005
3	baicaleinIBA 09/2014 - 04/2009
3	Fluorescein (Funduscein)FDA LinkGeneric 08/2014 - 05/2003
3	FibrinIBA 01/2014 - 08/2005
3	theasinensin AIBA 02/2012 - 05/2011
3	Histone Deacetylases (Histone Deacetylase)IBA 02/2012 - 05/2011
2	Biological ProductsIBA 05/2022 - 12/2021
2	AlkaloidsIBA 05/2022 - 10/2021
2	Cyclic NucleotidesIBA 10/2021 - 08/2014
2	pterostilbeneIBA 04/2021 - 03/2021
2	auraptenIBA 07/2020 - 11/2019
2	IntegrinsIBA 05/2020 - 11/2019
2	Plasminogen Activators (Plasminogen Activator)IBA 10/2019 - 04/2012
2	PlatinumIBA 05/2018 - 12/2017
2	EnzymesIBA 03/2018 - 09/2015
2	Adenosine Triphosphate (ATP)IBA 01/2018 - 12/2002
2	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 01/2018 - 02/2016
2	Protein Kinase CIBA 01/2018 - 01/2014
2	Antineoplastic Agents (Antineoplastics)IBA 01/2018 - 12/2011
2	Troleandomycin (TAO)FDA Link 01/2017 - 01/2011
2	Coloring Agents (Dyes)IBA 01/2017 - 08/2002
2	p38 Mitogen-Activated Protein KinasesIBA 04/2016 - 01/2014
2	oxidized low density lipoproteinIBA 03/2016 - 02/2015
2	nobiletinIBA 02/2016 - 02/2016
2	flavoneIBA 02/2016 - 02/2016
2	Transcription Factors (Transcription Factor)IBA 01/2015 - 03/2010
2	TropoloneIBA 01/2015 - 01/2013
2	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2014 - 04/2009
2	gamma-Aminobutyric Acid (GABA)IBA 06/2014 - 09/2007
2	Plasminogen InactivatorsIBA 01/2014 - 08/2005
2	NF-kappa B (NF-kB)IBA 01/2014 - 03/2010
2	sulforaphaneIBA 06/2013 - 05/2013
2	Midazolam (Versed)FDA LinkGeneric 04/2013 - 03/2004
2	Transforming Growth Factors (Transforming Growth Factor)IBA 04/2012 - 08/2005

Therapy/Procedure

5	Therapeutics 09/2021 - 04/2011
2	Resuscitation 01/2019 - 12/2015
2	Oral Administration 01/2014 - 01/2011